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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f01ab099e161b5816fcd2ac79cb5a09335f7a66e609c11858d84b2512f93c45' 
  AND token = 'cjMiClCHbr5dIlTpQLW1BhAqrFOuKwQi5KG19oDDPR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}