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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6571fa6ca456c64cedf24d86fd89aa04f988a3b8cd97421d0baf3f8929de409' 
  AND token = 'zauU2WHv704WHKb4hBPGBALqoW4+myxv94mY7zuArfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}