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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d62de220cb30f1c2e59e0bbac183024d8a1e122e7ac70e40e7d40e5e3301677' 
  AND token = 'I+uMzOlGLHAbP24AO5FBgpHLyoB/4fsflc96nVGnsSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}