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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '409fd112b5c1a3a7c0122466bc3a0526d806dbd74cc049c99b426e7c572cbbbe' 
  AND token = 'lAezGb7pdHDAaA9nAsWVlxsr/rKLmhVMCzd55h72rJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}