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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8ea9657f3fe0744c680880850b35e6a72b087ccb3ade036b74f24f48564eff' 
  AND token = '4Y8Ev8N0calsrB+nW7uUzJ/+qk2VySdMcx9pR9/epEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}