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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e12e3d9795ca133b9161e7ae282eb26d51b213ffbe4fd83ad4f5c0685d2de2eb' 
  AND token = 'S8R5P0lmSxuHlIS5P4N8YeNUj516JAcLONCnmbOAPkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}