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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d76ed4078e5eb6d0db68f2db9214cb010dabd85ca02e5fbe8d1258472ef5456' 
  AND token = '67uKTHvu9fB0ngsdp/r1BdZUQ3sG3QwV3mJcKaA+KFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}