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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e9088379ea5d9614737b79745a0a463e2b74de3b0bc284b803f6ffd476d224' 
  AND token = 'cDdWi/ILK2V97/FFcVbQLDRGmeuZxto6uVoFlD7/Im4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}