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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c744ae50fa16b33f809fb1312b300638ed9778b1931893525f4652d9759538e5' 
  AND token = 'MLw0l9aEcKGUs1rU6oWtyD9mR3oRujxTBgPX6JNsEUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}