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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379c6a70cf22656a58de923bbf19112c54247ebf76aebe9871ad58807bfb0781' 
  AND token = 'Hm1QO58VFIhzPsWFIj6DfGxR/nAKfPeIfzBAPG0r+08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}