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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb8a2eab27ce43d40530ac88083d06bb490174f1e4727ebaf1b1bd69d197542' 
  AND token = 'SLn8IlqzE1S1rbXSSw/AkZkHUbzDElb7aBYC4c6bZa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}