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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb9c2078164be7db80b591d566435a721ef28f21bab06187e5fa1f376a861e1' 
  AND token = 'yH5U3LUpM+qc6mvEN1P8v0euyeRkE4e/N9afgJoZ878=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}