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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '954f708dcd0460b5e149adf85717fbc6edd1c4698fb1e51d2e3c5a307e8328c2' 
  AND token = 'pfOdww96cyL1pnk8EMQKGcc/prAshz22Fv6Z9Vq0Mtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}