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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e2e4a6f58481412ea6a34747a7f7ebf500ffa14efd3029d923d679d01451e9' 
  AND token = '0bywEpHpzAR38xtC06/ES3En8qGM8msaCncUtHMehYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}