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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd81cbdefedda0aa3a02689af2b06cd534d1839ad50af1906e68eaa9aae7fb14' 
  AND token = 'PeDVHSkIp9xgDkOb9tALNDgFA66s3MMkZMOv02Y9mGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}