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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d3df9091273130c800cd09d36eeec1789cd952264bf7e86e6b0a00b5b17255' 
  AND token = 'IIRUbyu1F66DTP4rkQ057E0GbRCEArhwqshNu7JzSZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}