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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ead2159ef9d2702db82265a04cafdb6b19e391b5f2d5e53f15b31308f65f9c50' 
  AND token = '/G9sv1jWlHJVA60HxW8B4CKzHcMoPTx4neiMkSPwZMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}