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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf20b3db7da49e2bbd44f1a8dc62e57c7518b3f267adb9cbf1510d8d373fb550' 
  AND token = 'uEfJfj9LZPyaxLQVZObHiXPDvaqh2sbbDdWUw0xsl9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}