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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '955a5dea97f55b719cc58a9ad9ca6f9cf55bd6caf0ce310ae7065d85f8a5fd53' 
  AND token = 'aRFgU3iXonlAAr+6EVnkk3OCMs2wZCB+ufkDo2Gbats=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}