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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fd7d366b7676eb2d566529e1b9d02156865f928bb8bd4b10379545ed02e4346' 
  AND token = 'u/28Ll1k+3dh9a3mSTjiAgUKdTh/7318WLDN8Zmg0kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}