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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c88fc7ec8ba72c4c3bd5c4c0f603b3c20b48da5918385e95f56faac8b07cd8d' 
  AND token = 'jqkYiZzc2qh9v2S/MDbcuvY6GHNmD6hlI0HnsXYTdhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}