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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f428cdba2dca91fd7ec2a00f9f32da1715d943d0ad1d4b688938a0742fef7720' 
  AND token = 'vtzh6Owh7iOXVVPbQor8uQRKSdvDs3IQK9fN4MYh//0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}