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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a96815fb9b2cee72d06c62a77b20b236efe2d73b332322dae1e36ddef10b56' 
  AND token = 'LVZRk+ayB+024PwQ2q4JE/j8aa+XIj4zGZ/jTtmhWeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}