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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e1090680d0779ec7a7da07427ff197e0e35b7bf2ab56bbe3acf0d7bb5665b85' 
  AND token = 'jJTPFozV9xhdrOYfQ/edMYW2/SzPiVKXDKwTUWf3Mkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}