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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5696c6a9ec79a5ee448b3d26143ce990069cc33415edc7f6f100b36fd020697' 
  AND token = 'v4TIh3WLyE3LW1Plq1VdTT9Jg7RIJqYPDzESLlgQpg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}