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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac0bbcd2bdc8b7e8d83014eee45be56f3f8473465782a099c43a2467e17ae0b' 
  AND token = 'YB4RsY6K+fp0qCPXCHkTjwBJAv6s6UPPUErrJ9oBlio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}