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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63a8667134c52fc5bc95703907a164b3f195adf3c4a445ce8f31dbd2e7e6edff' 
  AND token = 'M+T+idgqpqY01p4XPqq618xJFa/Bf6GLcW1TLLuQbOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}