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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306cd837ac554e5a84d07e41ad15bc034113807d3b1c654e2552f14aec614436' 
  AND token = 'Oy3BfEpFI9aShIeU9HNZt74UAZLzNH28W5H2vNjvV4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}