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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db50b73d9e56c3ce3e2ba780418c478d7af3c69c00a0f3e73396c618ed988c4' 
  AND token = 'fOzdJZK+p9wjUCq9cyHMe4AYb9DwsEV19EThGpB0KnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}