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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5fc1ff85b378f7d51d3c7899d87d83c4a795e35b5c74f8b216aedf7ce96e7a6' 
  AND token = 'MwaUIOeKWTliyB7JSaF/L14/78rDWfx7q2QJSWeqZ9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}