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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de8ac7127d9758d85a0a5c6157582a5fb943b9bec444fed3eba7d06d37931408' 
  AND token = 'qHR+O0vp7FAkv3Tug2oUj7e4gm0+B/xmkHoQnejweAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}