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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5fd16f4c1db807c02a57d529f748128db8611230d1fdc212b215a9af0547bd' 
  AND token = '3M2JLfUf/s6rRMZKK/PxWcmU2hQLXHV2dYacMUFheuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}