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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35bafb265bdb8705f7246ab71865eee5ffe9abf9187bfba153ba23e0acb4f731' 
  AND token = 'VkFN1fykNDsgnhOavQbeVlFAGm36ZKizqAD16zb3ye8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}