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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e4c70729a42d733f7a6d41b87e43b256f13ad5fb1e4471d1d4b091d6d73959' 
  AND token = 'ULwz8tHeWT/MZ/PpczV3gUMHXEtMPrGrmgn2iHv61zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}