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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c67e252ac227c3592ebab7d31f8e6fe6660155ef9c1e293d86e01e93d94a4a17' 
  AND token = 'w206Mh7JC9dDiEx+T8iBb9LMMwzi+qgCi3MvWSqDLQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}