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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43542fb57e61c91f0e3237bd02020aa6797a2d1b1e7feb8456932f9e3044817e' 
  AND token = 'qM0l0kJLhei10VIYLYWu2TvXVRXeYVa3Mr9VvRwrXpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}