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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2544d107177d7b243c3b788e5eb784ade6cf557f7b4726228c2c95c1c1a5fb45' 
  AND token = 'KhNGsW7gWamh7clTdgW84nS0XBy93M/CP+7POJwtY3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}