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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e435c6b1a852f132f6b969565e63b844337447668bc7af7485d5ae92735323b3' 
  AND token = '604MEPjyljkKMic1aP6l2Az4d9bG7+x492U/IPSbPdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}