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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9e3194ffbccb2de4ef971646d9e83a8f427ea62b3ffca252d4da29a2e25a576' 
  AND token = 'CM2RyW6tvSkczvDwNk9lYH50IYXp/v+M7yGQ6Sxmzmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}