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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc95683667f6640f2fcefd3ea028350c9b4ff3c4c438e76ece813a2c7ee422e' 
  AND token = 'QG+tAmm/W5AfPG8+/q2g+TgoREDlcsqQ+zhgkk5SkcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}