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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38af2e5b187f6d3d92285ace6f38e4f4c06fc967f7d09504da0c821376096248' 
  AND token = 'LDXyh3znvz/itZbNTkfDqDhQaTIXZQUTZ6lx3Nu3u2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}