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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fa2cd7af378f8f345bbb9fda4adf6e90f6836093502df8d73d2f5c0af1fc2f' 
  AND token = 'MrdDAO0z39joQP5WT4vL4ohGzcGEYGRvTwiTwAdEeqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}