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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e7d0cfd0463afd186350f23da5f326c5dfa45d29763bab29724ab15f40e8de' 
  AND token = 'l0+f0tZ2goLbf2Fji5lhZTBTBin0/3HXXlP9eeBXoj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}