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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bb82253d5cedddaf11e0e1c6cc7fb64d9b873cdd4831a294bf24b6fa005333' 
  AND token = 'Xibpo+PZo6pgpQeKR3/d8t1I8V1F+OJfr4OTu9Db5VQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}