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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a0c8d53dfce70453d1c9f3e8acc9f6300a9e1014097110929da16d878466c5f' 
  AND token = 'SbaeOo1ZVR1LwEuMG9oFZWYFzlTsQkPOlaxM0zhY18o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}