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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93ea28a4a4c80b857a3b1d0fc04ef6dae20ce62243511a91d52ed84265584508' 
  AND token = '+bAzenlDBEFPpU6Z7ZTR/1zC2HV+XtpoXJBUNEVR6zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}