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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50521dfb8bcdc14e346bb0454ad4a210a4e4be33775f6aa4c52a834a8a4bd7fe' 
  AND token = 'ZuljuWiZeHgeJk7UcEHPtcuQZCQhXnq61Swx7qM7jfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}