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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd789e39dadf63158094bb01f44dd65b7bc4fb09012da20e7be036c1900497086' 
  AND token = 'mZpZKt/8Qpt4EOhX8Sc0X8BEozWi1Y9dKRvXG6N44DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}