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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45807a33e957c5372bc7a81aa7dfa73e6e48b3821a1148974f334e2bbbc63f2' 
  AND token = 'bfmgbfBvL/Ik/8gQWHirnXnvMt8Cv/X3l9VhWTdAlNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}