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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c944fb86cddf1bb70093e992482eceedcdb3b5937c4c38b74328c13ca0102968' 
  AND token = 'ObUM7KqdpUKto6MM342LFTBepeYZc5+bCwhcUD2YTow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}